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Dietary glucosylceramide is absorbed into the lymph and increases levels of epidermal sphingolipids

  • Junko Ishikawa

      Affiliations

    • Corresponding Author InformationCorresponding author. Tel.: +81 285 68 7491; fax: +81 285 68 7360.

Received 13 January 2009 Published online 12 July 2010 Corrected Proof

References 

  1. Asai S, Miyachi H. Evaluation of skin-moisturizing effects of oral or percutaneous use of plant ceramides. Rinsho Byori. 2007;55:209–215
  2. Tsuji K, Mitsutake S, Ishikawa J, Takagi Y, Akiyama M, Shimizu H, et al. Dietary glucosylceramide improves skin barrier function in hairless mice. J Dermatol Sci. 2006;44:101–107
  3. Kimata H. Improvement of atopic dermatitis and reduction of skin allergic responses by oral intake of konjac ceramide. Pediatr Dermatol. 2006;23:386–389
  4. Miyanishi K, Shiono N, Shirai H, Dombo M, Kimata H. Reduction of transepidermal water loss by oral intake of glucosylceramides in patients with atopic eczema. Allergy. 2005;60:1454–1455
  5. Nilsson A. Metabolism of cerebroside in the intestinal tract of the rat. Biochim Biophys Acta. 1969;187:113–121
  6. Renkonen O, Hirvisalo EL. Structure of plasma sphingadienine. J Lip Res. 1969;10:687–693
  7. Ando S, Isobe M, Nagai Y. High performance preparative column chromatography of lipids using a new porous silica, Iatrobeads. I. Separation of molecular species of sphingoglycolipids. Biochim Biophys Acta. 1976;424:98–105
  8. Colsch B, Afonso C, Popa I, Portoukalian J, Fournier F, Tabet JC, et al. Characterization of the ceramide moieties of sphingoglycolipids from mouse brain by ESI-MS/MS: identification of ceramides containing sphingadienine. J Lip Res. 2004;45:281–286
  9. Sugawara T, Kinoshita M, Onishi M, Nagata J, Saito M. Digestion of maize sphingolipids in rats and uptake of sphingadienine by Caco-2 cells. J Nutr. 2003;133:2777–2782

PII: S0923-1811(09)00274-6

doi: 10.1016/j.jdermsci.2009.09.002

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