Journal of Dermatological Science
Volume 58, Issue 1 , Pages 75-77 , April 2010

Decreased fibroblast contractile activity and reduced fibronectin expression are involved in skin photoaging

  • Anja Knott

      Affiliations

    • These authors have contributed equally to this work.
    • Corresponding Author InformationCorresponding author at: Beiersdorf AG, R&D – Research Skin Care, Bf. 519, Unnastrasse 48, 20245 Hamburg, Germany. Tel.: +49 40 4909 6215; fax: +49 40 4909 6770.
    • ,
  • Astrid Denckhan

      Affiliations

    • These authors have contributed equally to this work.
    • ,
  • Katja Reuschlein

Received 28 July 2009

References 

  1. Fisher GJ, Varani J, Voorhees JJ. Looking older: fibroblast collapse and therapeutic implications. Arch Dermatol. 2008;144(5):666–672
  2. Kligman LH. Photoaging, manifestations, prevention and treatment. Clin Geriatr Med. 1989;5(1):235–251
  3. Gilchrest BA. Age-associated changes in the skin. J Am Geriatr Soc. 1982;30:139–143
  4. Freyman TM, Yannas IV, Pek YS, Yokoo R, Gibson LJ. Micromechanics of fibroblast contraction of a collagen–GAG matrix. Exp Cell Res. 2001;269(1):140–153
  5. Dallon JC, Ehrlich P. A review of fibroblast-populated collagen lattices. Wound Rep Reg. 2008;16:472–479
  6. Hocking DC, Sottile J, Langenbach KJ. Stimulation of integrin-mediated cell contractility by FN polymerization. J Biol Chem. 2000;275(14):10673–10682
  7. Halliday NL, Tomasek JJ. Mechanical properties of the extracellular matrix influence FN fibril assembly in vitro. Exp Cell Res. 1995;217(1):109–117
  8. Chen M, Petersen MJ, Li HL, Cai XY, O’Toole EA, Woodley DT. Ultraviolet A irradiation upregulates type VII collagen expression in human dermal fibroblasts. J Invest Dermatol. 1997;108(2):125–128
  9. Yoshida Y, Kang K, Chen G, Gilliam AC, Cooper KD. Cellular fibronectin is induced in ultraviolet-exposed human skin and induces IL-10 production by monocytes/macrophages. J Invest Dermatol. 1999;113(1):49–55
  10. Stäb F, Wolber R, Blatt T, Keyhani R, Sauermann G. Topically applied antioxidants in skin protection. Methods Enzymol. 2000;319:465–478

PII: S0923-1811(10)00048-4

doi: 10.1016/j.jdermsci.2010.02.004

Journal of Dermatological Science
Volume 58, Issue 1 , Pages 75-77 , April 2010

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