Journal of Dermatological Science
Volume 59, Issue 2 , Pages 145-147 , August 2010

Measuring mRNA level expression of tumor necrosis factor α and its receptors related genes in patients with systemic sclerosis

  • A. Lis-Święty

      Affiliations

    • Corresponding Author InformationCorresponding author. Tel.: +48 602720948; fax: +48 322561182.

Received 14 April 2010

References 

  1. Lis-Święty A, Brzezińska-Wcisło L. Serum soluble tumor necrosis factor α receptor type I measurement in patients with Raynaud's phenomenon and systemic sclerosis. Post Dermatol Alergol. 2007;2(4):171–177
  2. Ramirez F, Tanaka S, Bou-Gharios G. Transcriptional regulation of the human alpha2(I) collagen gene (COL1A2), an informative model system to study fibrotic diseases. Matrix Biol. 2006;25:365–372
  3. Koenig M, Joyal F, Fritzler MJ, Roussin A, Abrahamowicz M, Boire G, et al. Autoantibodies and microvascular damage are independent predictive factors for the progression of Raynaud's phenomenon to systemic sclerosis: a twenty-year prospective study of 586 patients, with validation of proposed criteria for early systemic sclerosis. Arthritis Rheum. 2008;58:3902–3912
  4. Valentini G, Della Rossa A, Bombardieri S, Bencivelli W, Silman AJ, D’Angelo S, et al. European multicentre study to define disease activity criteria for systemic sclerosis. II. Identification of disease activity variables and development of preliminary activity indexes. Ann Rheum Dis. 2001;60:592–598
  5. Woszczyk D, Gola J, Jurzak M, Mazurek U, Mykała-Cieśla J, Wilczok T. Expression of TGFbeta 1 genes and their receptor types I, II, and III in low- and high-grade malignancy non-Hodgkin's lymphomas. Med Sci Monitor. 2004;10(1):CR33–CR37
  6. Young V, Ho M, Vosper H, Belch JJ, Palmer CN. Elevated expression of the genes encoding TNF-alpha and thromboxane synthase in leucocytes from patients with systemic sclerosis. Rheumatology (Oxford). 2002;41:869–875
  7. Askew D, Zhou L, Wu C, Chen G, Gilliam AC. Absence of cutaneous TNFalpha-producing CD4+ T cells and TNFalpha may allow for fibrosis rather than epithelial cytotoxicity in murine sclerodermatous graft-versus-host disease, a model for human scleroderma. J Invest Dermatol. 2007;127:1905–1914
  8. Carbone LD, Warrington KJ, Barrow KD, Pugazhenthi M, Watsky MA, Somes G, et al. Pamidronate infusion in patients with systemic sclerosis results in changes in blood mononuclear cell cytokine profiles. Clin Exp Immunol. 2006;146:371–380
  9. Fujita M, Shannon JM, Morikawa O, Gauldie J, Hara N, Mason RJ. Overexpression of tumor necrosis factor-alpha diminishes pulmonary fibrosis induced by bleomycin or transforming growth factor-beta. Am J Respir Cell Mol Biol. 2003;29:669–676
  10. Chizzolini C, Parel Y, De Luca C, Tyndall A, Akesson A, Scheja A, et al. Systemic sclerosis Th2 cells inhibit collagen production by dermal fibroblasts via membrane-associated tumor necrosis factor alpha. Arthritis Rheum. 2003;48:2593–2604

PII: S0923-1811(10)00192-1

doi: 10.1016/j.jdermsci.2010.05.008

Journal of Dermatological Science
Volume 59, Issue 2 , Pages 145-147 , August 2010

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