Journal of Dermatological Science
Volume 59, Issue 2 , Pages 123-128 , August 2010

Structural and functional differences in barrier properties of African American, Caucasian and East Asian skin

  • Neelam Muizzuddin

      Affiliations

    • Estée Lauder Companies, Research Park, Melville, NY, USA
    • ,
  • Lieveke Hellemans

      Affiliations

    • Estée Lauder Companies, Oevel, Belgium
    • Current address: Katholieke Hogeschool Kempen, Vorselaar, Belgium.
    • ,
  • Luc Van Overloop

      Affiliations

    • Estée Lauder Companies, Oevel, Belgium
    • ,
  • Hugo Corstjens

      Affiliations

    • Estée Lauder Companies, Oevel, Belgium
    • Corresponding Author InformationCorresponding author at: Estée Lauder Companies, Biological Research Department Europe, Nijverheidsstraat 15, 2260 Oevel, Belgium. Tel.: +32 14 25 89 04.
    • ,
  • Lieve Declercq

      Affiliations

    • Estée Lauder Companies, Oevel, Belgium
    • ,
  • Daniel Maes

      Affiliations

    • Estée Lauder Companies, Research Park, Melville, NY, USA

Received 21 July 2009 ,Revised 7 June 2010 ,Accepted 14 June 2010.

References 

  1. Stepanova EV, Strube MJ. Making of a face: role of facial physiognomy, skin tone, and color presentation mode in evaluations of racial typicality. J Soc Psychol. 2009;149:66–81
  2. Sturm RA. Molecular genetics of human pigmentation diversity. Hum Mol Genet. 2009;18:R9–17
  3. Wilson D, Berardesca E, Maibach HI. In vitro transepidermal water loss: differences between black and white skin. Br J Dermatol. 1988;199:647–652
  4. Berardesca E, Rigal J, Leveque JL. In vivo biophysical characterization of skin physiological differences in races. Dermatologica. 1991;182:89–93
  5. Sugino K, Imokawa G, Maibach HI. Ethnic difference of stratum corneum lipid in relation to stratum corneum function. J Invest Dermatol. 1993;100:587
  6. Diridollou S, de Rigal J, Querleux B, Leroy F, Holloway Barbosa V. Comparative study of the hydration of the stratum corneum between four ethnic groups: influence of age. Int J Dermatol. 2007;46:11–14
  7. Fotoh C, Elkhyat A, Mac S, Sainthillier JM, Humbert P. Cutaneous differences between Black, African or Caribbean mixed-race and Caucasian women: biometrological approach of the hydrolipidic film. Skin Res Technol. 2008;14:327–335
  8. Rawlings AV. Ethnic skin types: are there differences in skin structure and function?. Int J Cosmet Science. 2006;28:79–93
  9. Wesley NO, Maibach HI. Racial (ethnic) differences in skin properties: the objective data. Am J Clin Dermatol. 2003;4:843–860
  10. Gunathilake R, Schurer NY, Shoo BA, Celli A, Hachem JP, Crumrine D, et al. pH-regulated mechanisms account for pigment-type differences in epidermal barrier function. J Invest Dermatol. 2009;129:1719–1729
  11. Berardesca E, Maibach H. Racial differences in skin pathophysiology. J Am Acad Dermatol. 1996;34:667–672
  12. Kligman AM, Sadiq I, Zhen Y, Crosby M. Experimental studies on the nature of sensitive skin. Skin Res Technol. 2006;12:217–222
  13. Farage MA. Perceptions of sensitive skin: changes in perceived severity and associations with environmental causes. Contact Dermatitis. 2008;59:226–232
  14. Kompaore F, Marty JP, Dupont C. In vivo evaluation of the stratum corneum barrier function in blacks, Caucasians and Asians with two noninvasive methods. Skin Pharmacol. 1993;6:200–207
  15. Wang H, Papoiu A, Coghill R, Patel T, Yosipovitch G. African Americans display a significant lack of hyperalgesia and neurogenic inflammation in response to topical capsaicin. J Invest Dermatol. 2009;129:S52
  16. OMB directive dd. 30.10.1997; http://www.whitehouse.gov/omb/fedreg_1997standards/.
  17. Muizzuddin N, Marenus K, Maes D. Factors defining sensitive skin and its treatment. Am J Cont Derm. 1998;9:170–175
  18. Marenus K, Maes D, Muizzuddin N, Stoudemeyer T, Kligman A. Testing skin care and cosmetic products at high resolution to establish comfort. J.S.C.C. 1998;48:63–65
  19. Feingold KR. The role of epidermal lipids in cutaneous permeability barrier homeostasis. J Lipid Res. 2007;48:2531–2546
  20. Bouwstra JA, Ponenc M. The skin barrier in healthy and diseased state. Biochim Biophys Acta. 2006;12:2080–2095
  21. Harding CR, Long S, Richardson J, Rogers J, Zhang Z, Bush A, et al. The cornified cell envelope: an important marker for stratum corneum maturation in healthy and dry skin. Int J Cosmet Sci. 2003;25:1–11
  22. Egelrud T, Lundström A. A chymotrypsin-like proteinase that may be involved in desquamation in plantar stratum corneum. Arch Dermatol Res. 1991;283:108–112
  23. Declercq L, Van Overloop L, Hellemans L, Corstjens H, Maes D. Detection of cis-urocanic acid in stratum corneum as a biological marker for UV exposure in human volunteer studies. In: “Gordon research conference on barrier function of mammalian skin”. Newport, RI, USA. 2007;
  24. Grubauer G, Elias PM, Feingold KR. Transepidermal water loss: the signal for recovery of barrier structure and function. J Lipid Res. 1989;30:323–333
  25. Elias PM. Epidermal lipids, barrier function, and desquamation. J Invest Dermatol. 1983;80:044s–049s
  26. Meguro S, Arai Y, Masukawa Y, Uie K, Tokimitsu I. Relationship between covalently bound ceramides and transepidermal water loss. Arch Dermatol Res. 2000;292:463–468
  27. Watkinson A, Harding C, Moore A, Coan P. Water modulation of stratum corneum chymotryptic enzyme activity and desquamation. Arch Dermatol Res. 2001;293:470–476
  28. Caubet C, Jonca N, Brattsand M, Guerrin M, Bernard D, Schmidt Ret al. Degradation of corneodesmosome proteins by two serine proteases of the kallikrein family, SCTE/KLK5/hK5 and SCCE/KLK7/hK7. J Invest Dermatol. 2004;122:1235–1244
  29. Akutsu N, Ooguri M, Onodera T, Kobayashi Y, Katsuyama M, Kunizawa N, et al. Functional characteristics of the skin surface of children approaching puberty: age and seasonal influences. Acta Derm Venereol. 2009;89:21–27
  30. Muizzuddin N, Marenus KD, Schnittger SF, Sullivan M, Maes DH. Effect of systemic hormonal cyclicity on skin. J Cosmet Sci. 2005;56:311–321
  31. Garg A, Chren M, Sands L, Matsui M, Marenus K, Feingold K, et al. Psychological stress perturbs epidermal permeability barrier homeostasis: implications for the pathogenesis of stress-associated skin disorders. Arch Dermatol. 2001;137:53–59
  32. Halkier-Sørensen L, Menon GK, Elias PM, Thestrup-Pedersen K, Feingold KR. Cutaneous barrier function after cold exposure in hairless mice: a model to demonstrate how cold interferes with barrier homeostasis among workers in the fish-processing industry. Br J Dermatol. 1995;132:391–401
  33. Steinert PM, Marekov LN. Initiation of assembly of the cell envelope barrier structure of stratified squamous epithelia. Mol Biol Cell. 1999;10:4247–4261
  34. Hirao T, Denda M, Takahashi M. Identification of immature cornified envelopes in the barrier-impaired epidermis by characterization of their hydrophobicity and antigenicities of the components. Exp Dermatol. 2001;10:35–44
  35. Maes D, Van Overloop L, Corstjens H, Declercq L. The maturation index: the ultimate differentiation marker. In: Proceedings of the 25th IFSCC congress. 2008;
  36. Richards GM, Oresajo CO, Halder RM. Structure and function of ethnic skin and hair. Dermatol Clin. 2003;21:595–600
  37. Castiel-Higounenc I, Chopart M, Ferraris C. In: Stratum corneum lipids: specificity, role, deficiencies and modulation. 11:OCL-OL Corps Gras Li; 2004;p. 401–406
  38. Jin K, Higaki Y, Takagi Y, Higuchi K, Yada Y, Kawashima M, et al. Analysis of betaglucocerebrosidase and ceramidase activities in atopic and aged dry skin. Acta Derm Venereol. 1994;74:337–340
  39. Declercq L, Muizzuddin N, Hellemans L, Van Overloop L, Sparacio R, Marenus K, et al. Adaptation response in human skin barrier to a hot and dry environment. J Invest Dermatol. 2002;119:716
  40. Van Overloop L, Declercq L, Maes D. Visual scaliness of human skin correlates to decreased ceramide levels and decreased stratum corneum protease activity. J Invest Dermatol. 2001;117:811
  41. Santanastasio H, Zhang S, Krishnan S, Velthuizen R, Shah P, Tsaur L. Quantifying skin ashing using cross-polarized imaging. Skin Res Technol. 2003;9:194

PII: S0923-1811(10)00195-7

doi: 10.1016/j.jdermsci.2010.06.003

Journal of Dermatological Science
Volume 59, Issue 2 , Pages 123-128 , August 2010

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