Journal of Dermatological Science
Volume 60, Issue 1 , Pages 52-54 , October 2010

Serum TARC/CCL17 levels are increased in dermatomyositis associated with interstitial lung disease

  • Tomohiko Kawashima

      Affiliations

    • Department of Dermatology, Faculty of Medicine, University of Tokyo, Tokyo, Japan
  • ,
  • Yayoi Tada

      Affiliations

    • Department of Dermatology, Faculty of Medicine, University of Tokyo, Tokyo, Japan
    • Corresponding Author InformationCorresponding author at: Department of Dermatology, Faculty of Medicine, University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113 8655, Japan, Tel.: +81 3 5800 8661; fax: +81 3 3814 1503.
  • ,
  • Yoshihide Asano

      Affiliations

    • Department of Dermatology, Faculty of Medicine, University of Tokyo, Tokyo, Japan
  • ,
  • Norihito Yazawa

      Affiliations

    • Department of Dermatology, Faculty of Medicine, University of Tokyo, Tokyo, Japan
  • ,
  • Manabu Tomita

      Affiliations

    • Department of Dermatology, Faculty of Medicine, University of Tokyo, Tokyo, Japan
  • ,
  • Zenshiro Tamaki

      Affiliations

    • Department of Dermatology, Faculty of Medicine, University of Tokyo, Tokyo, Japan
  • ,
  • Masahide Kubo

      Affiliations

    • Department of Dermatology, Faculty of Medicine, University of Tokyo, Tokyo, Japan
  • ,
  • Hironobu Ihn

      Affiliations

    • Department of Dermatology and Plastic Surgery, Faculty of Life Sciences, Kumamoto University, Kumamoto, Japan
  • ,
  • Makoto Sugaya

      Affiliations

    • Department of Dermatology, Faculty of Medicine, University of Tokyo, Tokyo, Japan
  • ,
  • Takafumi Kadono

      Affiliations

    • Department of Dermatology, Faculty of Medicine, University of Tokyo, Tokyo, Japan
  • ,
  • Kunihiko Tamaki

      Affiliations

    • Department of Dermatology, Faculty of Medicine, University of Tokyo, Tokyo, Japan
  • ,
  • Shinichi Sato

      Affiliations

    • Department of Dermatology, Faculty of Medicine, University of Tokyo, Tokyo, Japan

Received 2 June 2010

References 

  1. Bohan A, Peter JB . Polymyositis and dermatomyositis (first of two parts). N Engl J Med. 1975;292(7):344–347
  2. Bohan A, Peter JB . Polymyositis and dermatomyositis (second of two parts). N Engl J Med. 1975;292(8):403–407
  3. Belperio JA, Dy M, Murray L, Burdick MD, Xue YY, Strieter RM, et al. The role of the Th2 CC chemokine ligand CCL17 in pulmonary fibrosis. J Immunol. 2004;173(7):4692–4698
  4. Ritter M, Goggel R, Chaudhary N, Wiedenmann A, Jung B, Weith A, et al. Elevated expression of TARC (CCL17) and MDC (CCL22) in models of cigarette smoke-induced pulmonary inflammation. Biochem Biophys Res Commun. 2005;334(1):254–262
  5. Kishi M, Miyazaki Y, Jinta T, Furusawa H, Ohtani Y, Inase N, et al. Pathogenesis of cBFL in common with IPF? Correlation of IP-10/TARC ratio with histological patterns. Thorax. 2008;63(9):810–816
  6. Trujillo G, O’Connor EC, Kunkel SL, Hogaboam CM. A novel mechanism for CCR4 in the regulation of macrophage activation in bleomycin-induced pulmonary fibrosis. Am J Pathol. 2008;172(5):1209–1221
  7. Fujii H, Shimada Y, Hasegawa M, Takehara K, Sato S. Serum levels of a Th1 chemoattractant IP-10 and Th2 chemoattractants, TARC and MDC, are elevated in patients with systemic sclerosis. J Dermatol Sci. 2004;35(1):43–51
  8. Nakajima H, Harigai M, Hara M, Hakoda M, Tokuda H, Sakai F, et al. KL-6 as a novel serum marker for interstitial pneumonia associated with collagen diseases. J Rheumatol. 2000;27(5):1164–1170
  9. Takahashi H, Fujishima T, Koba H, et al. Serum surfactant proteins A and D as prognostic factors in idiopathic pulmonary fibrosis and their relationship to disease extent. Am J Respir Crit Care Med. 2000;162(3 Pt 1):1109–1114
  10. Ihn H, Asano Y, Kubo M, Yamane K, Jinnin M, Yazawa N, et al. Clinical significance of serum surfactant protein D (SP-D) in patients with polymyositis/dermatomyositis: correlation with interstitial lung disease. Rheumatology (Oxford). 2002;41(11):1268–1272

PII: S0923-1811(10)00234-3

doi: 10.1016/j.jdermsci.2010.07.012

Journal of Dermatological Science
Volume 60, Issue 1 , Pages 52-54 , October 2010