Journal of Dermatological Science
Volume 16, Issue 3 , Pages 226-230 , March 1998

Modulation of UVA light-induced oxidative stress by β-carotene, lutein and astaxanthin in cultured fibroblasts

Received 14 April 1997 ,Revised 16 June 1997 ,Accepted 8 July 1997.

References 

  1. Black HS, Chan JT. Suppression of ultraviolet light-induced tumour formation by dietary antioxidants. J Invest Dermatol. 1975;65:412–414
  2. Mathews-Roth MM, Krinsky NI. Carotenoids affect development of UVB-induced skin cancer. Photochem Photobiol. 1987;46:507–509
  3. Greenberg ER, Baron JA, Stukel TA, Stevens MM, Mandel JS, Spencer SK, et al. A clinical trial of beta carotene to prevent basal-cell and squamous cell cancers of the skin. N Engl J Med. 1990;323:789–795
  4. Thurnham DI. Carotenoids: functions and fallacies. Proc Nutr Soc. 1994;53:77–87
  5. Chopra M, Wilson RL, Thurnham DI. Free radical scavenging ability of lutein in vitro. In: Canfield LM, Krinsky NI, Olson JA, editors. Carotenoids in Human Health. New York: Ann NY Acad Sci, 1993:61–7.
  6. Kurashige M, Okimasu E, Inoue M, Utsumi K. Inhibition of oxidative injury of biological membranes by astaxanthin. Physiol Chem Phys Med NMR. 1990;22:27–38
  7. Palozza P, Krinsky NI. Astaxanthin and canthaxanthin are potent antioxidants in a membrane model. Arch Biochem Biophys. 1992;297:291–295
  8. Lawlor SM, O'Brien NM. Astaxanthin: antioxidant effects in chicken embryo fibroblasts. Nutr Res. 1995;15:1695–1704
  9. Lawlor SM, O'Brien NM. Development of an in vitro cell culture model to investigate the induction and quantification of oxidative stress and its inhibition by α-tocopherol. Toxicol In Vitro. 1994;8:67–73
  10. Lawlor SM, O'Brien NM. Modulation of oxidative stress by β-carotene in chicken embryo fibroblasts. Br J Nutr. 1995;73:841–850
  11. Wilson AM, Sisk RM, O'Brien MN. Modulation of cholestan-3β,5α,6β-triol toxicity by butylated hydroxytoluene, α-tocopherol and β-carotene in newborn rat kidney cells in vitro. Br J Nutr 1997;78:479–92.
  12. Vassault A. Lactate dehydrogenase. In: Bergmeyer HU, editor. Methods of Enzymatic Analysis. New York: Academic Press, 1983:118–26.
  13. Baudhuin P, Beaufay H, Rahman-Li Y, Sellinger OZ, Wattiaux R, Jacques P, et al. Tissue fractionation studies. Intracellular distribution of monoamine oxidase, aspartate aminotransferase, alanine aminotransferase, d-amino acid oxidase and catalase in rat liver tissue. Biochem J. 1964;92:179–184
  14. McCord JM, Fridovich I. Superoxide dismutase. An enzyme function for erythrocuprein (hemocuprein). J Biol Chem. 1969;244:6049–6055
  15. Sheehy PJA, O'Mahony E, O'Sullivan-Corbett K, Salvatella M. Simultaneous determination of retinol, α-, γ- and δ-tocopherol, 6 carotenoids and internal standards in plasma by reverse-phase HPLC. FLAIR Meeting, Montreaux, 1994.
  16. Bertram JS, Pung A, Churley M, Kappock TJ, Wilkins LR, Cooney RV. Diverse carotenoids protect against chemically induced neoplastic transformation. Carcinogene. 1991;12:671–678
  17. White WS, Kim C, Kalkwarf HJ, Bustos P, Roe DA. Ultraviolet light-induced reductions in plasma carotenoid levels. Am J Clin Nutr. 1988;47:879–883
  18. Mathews-Roth MM, Pathak MA, Fitzpatrick TB, Harber LH, Kass EH. Beta carotene therapy for erythropoietic protoprophyria and other photosensitivity diseases. Arch Dermatol. 1977;113:1229–1232
  19. Mathews-Roth MM, Krinsky NI. Carotenoids affect development of UVB induced skin cancer. Photochem Photobiol. 1987;46:507–509
  20. Fuller CJ, Faulkner H, Bendich A, Parker RS, Roe DA. Effect of β-carotene supplementation on photosuppression of delayed-type hypersensitivity in normal young men. Am J Clin Nutr. 1992;56:684–690

PII: S0923-1811(97)00058-3

Journal of Dermatological Science
Volume 16, Issue 3 , Pages 226-230 , March 1998

Article Tools