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Role of active oxygen species and antioxidants in photoaging
Abstract: The mechanism for the formation of active oxygen species and their reactions with antioxidants is described. The importance of the free radical chain oxidation and the singlet oxygen-depende...
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Yorihiro Yamamoto
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1-4
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Mechanical methods for evaluating skin surface architecture in relation to wrinkling
Abstract: Various methods have recently been developed to study skin surface micro-structures including wrinkles and these techniques have been frequently modified in the search for an appropriate and...
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Syuichi Akazaki,
Genji Imokawa
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5-10
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Pentosidine in advanced glycation end-products (AGEs) during UVA irradiation generates active oxygen species and impairs human dermal fibroblasts
Abstract: Our previous study reported that advanced glycation end-products (AGE)-modified BSA produced active oxygen species, O2−, H2O2, and OH under UVA irradiation and enhanced the cytotoxicity of U...
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Yuri Okano,
Hitoshi Masaki,
Hiromu Sakurai
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11-18
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Epidermal changes caused by chronic low-dose UV irradiation induce wrinkle formation in hairless mouse
Abstract: To investigate the effects of chronic low-dose UV irradiation on the skin, hairless mice were irradiated with a 1/3 minimal erythemal dose (MED) of UV. We examined the relationship between v...
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Hiroaki Kambayashi,
Masahiro Yamashita,
Yuki Odake,
Koji Takada,
Yoko Funasaka,
Masamitsu Ichihashi
et al.
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19-25
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Skin premature aging induced by tobacco smoking: the objective evidence of skin replica analysis
Abstract: Epidemiological studies have showed that heavy smoking causes premature skin aging. Using a silicone rubber replica combined with computerized image processing, an objective measurement of s...
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Lei Yin,
Akimichi Morita,
Takuo Tsuji
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26-31
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Ultrastructural characterization of microvasculature in photoaging
Abstract: The cutaneous microvasculature was examined by electron microscopy in order to compare its characteristics in photodamaged preauricular skin and in sun-protected postauricular sites of 15 Ja...
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Masahiko Toyoda,
Motokazu Nakamura,
Yu Luo,
Masaaki Morohashi
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32-41
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Quantitative evaluation of skin condition in an epidemiological survey of females living in northern versus southern Japan
Abstract: Image analysis and biophysical methods were used to compare the skin condition of a group of females ranging in age from 5 to 65 years who had lived all of their lives in either Kagoshima (n...
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Greg.G Hillebrand,
Kukizo Miyamoto,
Beverly Schnell,
Masamitsu Ichihashi,
Reiko Shinkura,
Suminori Akiba
et al.
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42-52
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The efficacy of glycolic acid for treating wrinkles: analysis using newly developed facial imaging systems equipped with fluorescent illumination
Abstract: The clinical characteristics of photodamaged skin, such as coarse and fine wrinkling, can not be quantitatively evaluated from ordinary photographic records. The purpose of this study was to...
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Yoko Funasaka,
Hirofumi Sato,
Akiko Usuki,
Akiko Ohashi,
Hisami Kotoya,
Kukizo Miyamoto,
Greg G. Hillebrand,
Masamitsu Ichihashi
et al.
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53-59
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New formulation of chemical peeling agent: histological evaluation in sun-damaged skin model in hairless mice
Abstract: Background: chemical peelings injure the superficial skin, which is then restored by healing of the wound. Objectives: to document the acute and chronic histological changes produced by appl...
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Midori Isoda,
Setsuko Ueda,
Shuhei Imayama,
Kazue Tsukahara
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60-67
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Effects of all-trans retinoic acid on melanogenesis in pigmented skin equivalents and monolayer culture of melanocytes
Abstract: The effects of all-trans retinoic acid (RA) on melanogenesis and the mechanism of its action in topical treatment have not been elucidated. The purpose of this study was to determine the eff...
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Kotaro Yoshimura,
Katsuhiko Tsukamoto,
Mutsumi Okazaki,
Victoria M. Virador,
Tie-Chi Lei,
Yasutoshi Suzuki,
Gentaro Uchida,
Yukie Kitano,
Kiyonori Harii
et al.
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68-75
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Author index
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76
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