This paper is only available as a PDF. To read, Please Download here.
Abstract
Marked disturbance of microcirculation was observed in 85 cases of dermatomyositis:
decrease in number and irregular pattern of the capillaries, many being tortuous and
dilated and having a slow and granular blood stream, as well as an increase of vascular
permeability. The changes were more marked in cases with visceral disorders, or in
active disease; however, there was no correlation between these changes and the duration
of illness. Blood hyperviscosity was found in an hemorrheological study. The cause
is considered to be due to high plasma viscosity, high fibrinogen levels, and increase
of aggregation of erythrocytes and platelets. Modulation of microcirculation is advisable
in the treatment of dermatomyositis.
Keywords
To read this article in full you will need to make a payment
Purchase one-time access:
Academic & Personal: 24 hour online accessCorporate R&D Professionals: 24 hour online accessOne-time access price info
- For academic or personal research use, select 'Academic and Personal'
- For corporate R&D use, select 'Corporate R&D Professionals'
Subscribe:
Subscribe to Journal of Dermatological ScienceAlready a print subscriber? Claim online access
Already an online subscriber? Sign in
Register: Create an account
Institutional Access: Sign in to ScienceDirect
References
- Skin capillaroscopy in connective tissue disease.Chinese J Med. 1978; 58: 757-760
- Skin capillary abnormalities as indicators of organ involvement in scleroderma (systemic sclerosis), Raynaud's syndrome and dermatomyositis.Am J Med. 1976; 61: 862-870
- Childhood dermatomyositis: serial microvascular studies.Pediatrics. 1989; 83: 278-283
- Studies on the mocrocirculation of the skin in disease.J Invest Dermatol. 1962; 39: 501-508
- Kapillaroskopische Untersuchungen bei Dermatomyositis und Lupus Erythematosus.Z Haut-Geschl Kr. 1972; 47: 509-510
- Multifunctional motile microcirculation microscope.J Clin Dermatol. 1983; 12: 41-42
- Platelet aggregation function in psoriasis.Shanghai Med J. 1990; 13: 233-234
- Juvenile Dermatomyositis: Histological findings and pathogenetic hypothesis for the associated skin changes.J Rheumatol. 1988; 12: 753-759
- SLE (IV) Vascular changes in SLE (1).Japanese J Clin Dermatol. 1980; 34: 68-72
- Observation on finger microcirculation and tongue tip microcirculation in systemic lupus erythematosus.Tienjin Med J. 1980; : 25-27
- Intérèt de la capillaroscopie périungéale dans le diagnostic précoce de la sclérodermie systémique.Ann Dermatol Venereol. 1983; 110: 11-20
- Quantification of the nail fold capillary abnormalities in systemic sclerosis and Raynaud's syndrome.Acta Derm Venereol (Stockh). 1986; 66: 139-143
- Are nailfold capillary changes indicators of organ involvement in progressive systemic sclerosis?.Dermatologica. 1988; 176: 18-21
- Capillary microscopy in the diagnosis of dermatologic diseases.J Invest Dermatol. 1954; 22: 199-206
- Polymyositis associated with cerebral thrombosis: a caes report.J Clin Dermatol. 1985; 14: 95
Article info
Publication history
Accepted:
April 16,
1991
Received:
June 19,
1990
Identification
Copyright
© 1991 Published by Elsevier Inc.
