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Abstract
A possible relationship between intestinal structure and function in the pathogenesis
of psoriasis has recently brought about considerable interest. The purpose of this
study was to evaluate the intestinal permeability in psoriatic patients by comparing
it with healthy controls. 15 psoriatic patients and 15 healthy volunteers entered
the study. Intestinal permeability was evaluated using the 51Cr-labeled EDTA absorption test. The 24-h urine excretion of 51Cr-EDTA from psoriatic patients was 2.46 ± 0.81%. These results differed significantly
from controls (1.95 ± 0.36%; P < 0.05). The difference in intestinal permeability between psoriatic patients and
controls could be due to alterations in the small intestinal epithelium of psoriatics.
Keywords
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Article info
Publication history
Accepted:
March 4,
1991
Received:
July 27,
1990
Identification
Copyright
© 1991 Published by Elsevier Inc.
