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Abstract
The purpose of this study was to compare the cholinergic responsiveness of the human
sweat gland in trained and untrained men. Eighteen healthy male volunteers (9 trained,
9 sedentary) served as subjects. Pilocarpine concentration vs. sweat rate dose-response
curves were obtained from each subject using iontophoresis. From these measurements,
maximal iontophoretic sweat rate (SRmax) was determined and correlated with each subject's maximal oxygen uptake (VO2max). The trained group had a significantly (P<0.05) greater mean SR max and their mean dose-response curve was shifted up and to
the left, as compared to the sedentary controls. Furthermore, VO2max was significantly correlated with SRmax (r = 0.76). These findings suggest that the modification occurring in the human sweat
gland after training may include improvements in both SRmax and cholinergic sensitivity, and support the hypothesis that the potentiation in
sweating following training is achieved via a peripheral mechanism.
Keywords
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Article info
Publication history
Accepted:
April 6,
1991
Received:
March 4,
1991
Identification
Copyright
© 1992 Published by Elsevier Inc.
