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Abstract
Human hair follicles, especially small vellus hair follicles, showed characteristic
structures as follows: (I) small vellus hair follicles were surrounded with skirt-like
epithelial structures or perifollicular connective tissue capsule; (II) perifollicular
clear space was present between the outer root sheath and skirt-like structure, or
the outer root sheath and perifollicular connective tissue capsule; (III) perifollicular
clear space was filled with a loose, alcian blue positive mucinous substance and elongated
fibroblasts and mast cells; (IV) perifollicular nerve endings were attached to the
follicular wall in a palisading arrangement within the clear space under the skirt;
(V) perifollicular nerve end organs and connective tissue capsule were positively
immunostained for CD34 and protein gene product 9.5 (PGP9.5). These specialized structures
of human small vellus hair follicles seem to correspond to the blood sinus of the
sinus hair follicles, where similar structural elements were found.
Keywords
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Article info
Publication history
Accepted:
December 12,
1994
Received in revised form:
November 18,
1994
Received:
September 14,
1994
Identification
Copyright
© 1995 Published by Elsevier Inc.