Abstract
The purpose of this study was to investigate the efficacy of phototherapy with a newly-developed
high-intensity, enhanced, narrow-band, blue light source in patients with mild to
moderate acne. An open study was performed in acne patients who were treated twice
a week up to 5 weeks. Acne lesions were reduced by 64%. Two patients experienced dryness.
No patient discontinued treatment due to adverse effects. In vitro investigation revealed
that irradiation from this light source reduced the number of Propionibacterium acnes (P. acnes), but not Staphylococcus epidermidis that were isolated from the acne patients. Phototherapy using this blue light source
was effective and well tolerated in acne patients and had an ability to decrease numbers
of P. acnes in vitro, suggesting that this phototherapy may be a new modality for the treatment
of acne.
Keywords
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Article info
Publication history
Accepted:
June 19,
2002
Received in revised form:
June 17,
2002
Received:
April 19,
2002
Identification
Copyright
© 2002 Elsevier Science Ireland Ltd. Published by Elsevier Inc. All rights reserved.
