Atopic dermatitis (AD) is a chronic inflammatory skin disease with a complex genetic
background. It belongs to the group of atopic disorders that are characterized by
a T helper (Th) type 2-dominated immune response. Recent evidence suggested that atopic
diseases and autoimmune disorders (which are mainly Th1-driven) may not be mutually
exclusive, but rather share certain risk factors that increase the development of
either Th1- or Th2-immune responses to non-pathogenic antigens [
[1]
].Keywords
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Article info
Publication history
Published online: July 12, 2010
Received:
February 3,
2009
Identification
Copyright
© 2009 Japanese Society for Investigative Dermatology. Published by Elsevier Inc. All rights reserved.