Proopiomelanocortin (POMC) is a prohormone produces various bioactive peptides via
a series of enzymatic steps in a tissue-specific manner, including adrenocorticotropin
(ACTH), α-melanocyte stimulating hormone (α-MSH), and β-endorphin. POMC is expressed
not only in the pituitary gland, but also in a variety of non-pituitary organs, including
the skin [
[1]
]. The functions of POMC-derived peptides in immunomodulation are still under investigation.Keywords
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References
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Article info
Publication history
Published online: July 12, 2010
Received:
January 15,
2009
Identification
Copyright
© 2009 Japanese Society for Investigative Dermatology. Published by Elsevier Inc. All rights reserved.
