Abstract
Background
Pigmentation induced by narrow-band UVB (NBUVB) phototherapy can cause complaints
by psoriasis patients, especially those with brown skin. Nevertheless, the recovery
process from tanning after the completion of NBUVB treatment is not known.
Objective
The purpose of this study was to evaluate the extent of tanning recovery after the
end of NBUVB treatment and determine the time required to recover from the fully tanned
state.
Method
Sixteen psoriasis patients with brown skin were observed. The skin color changes on
the lower back were measured before beginning phototherapy, upon completion of NBUVB
treatment, and subsequently every month for the first one-half year, then bimonthly
for the second one-half year, using two different reflectance spectrophotometers.
The results are presented as the erythema index (EI) and melanin index (MI), L*a*b* values as recommended by the Commission Internationale de l’Eclairge, and the individual
typology angle (ITA°).
Results
The mean L* value reached 64.4 by the 10th month after the end of NBUVB treatment, with no significant
difference from the value before beginning phototherapy. The mean ITA° approximated
the initial angle at the 8th month after completing NBUVB treatment with no significant
difference, thus representing recovery to the original intermediate skin color. The
MI recovered to the initial values earlier than the L* value and ITA°. The EI appeared the earliest recovery value.
Conclusion
Understanding the recovery process from tanning induced by NBUVB treatment will improve
the patient's compliance for treatment and bring higher efficacy and safety to the
retrial of phototherapy in brown-skinned individuals with psoriasis.
Keywords
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Article info
Publication history
Published online: July 12, 2010
Accepted:
October 3,
2009
Received in revised form:
August 9,
2009
Received:
March 10,
2009
Identification
Copyright
© 2009 Japanese Society for Investigative Dermatology. Published by Elsevier Inc. All rights reserved.
