Exposure of the skin to ultraviolet radiation (UVR) has many detrimental effects,
including sunburning/inflammation, photocarcinogenesis, and photoaging. Longwave ultraviolet
radiation (UVA) has long been considered less damaging than shortwave ultraviolet
radiation (UVB), but has since been recognized to be a complete carcinogen itself
[
[1]
], to be a particular cause of photoaging, and to elicit a number of inflammatory
photodermatoses. Cells are equipped to counteract the damaging effects of UVR and
respond to UVR by altering the expression of thousands of genes [
[2]
]. The changes of gene expression are wavelength specific, a reflection of the fact
that the cellular responses to UVA and UVB are profoundly different.To read this article in full you will need to make a payment
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Article info
Publication history
Published online: February 20, 2018
Accepted:
February 16,
2018
Received in revised form:
December 31,
2017
Received:
November 9,
2017
Identification
Copyright
© 2018 Japanese Society for Investigative Dermatology. Published by Elsevier B.V. All rights reserved.
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Access this article on ScienceDirectLinked Article
- Erratum to The UVA-induced long non-coding RNA GS1-600G8.5 regulates the expression of IL-8, J. Dermatol. Sci. 90 June (3) (2018) 363–366Journal of Dermatological ScienceVol. 91Issue 2
