Abstract
Human T-lymphotropic virus type I (HTLV-I) is thought to be the causative agent of
adult T-cell leukemia/lymphoma (ATL). This virus infection is endemic in southwestern
Japan, parts of Africa and the Caribbean Islands. We examined sera of 1645 subjects
of Liaoning province, northeastern China to detect HTLV-I carriers in an effort to
reveal the migratory route taken by the early Japanese (Jomon people). As a result,
all sera were found to be negative as tested by particle-agglutination (PA), immunofluorescence
(IF), enzyme-linked immunoabsorbent (ELISA) and Western blotting methods. This suggests
that the Jomon people, who are thought to have brought HTLV-I to the Japan archipelago
tens of thousands of years ago, did not come from northeast China.
Keywords
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Article info
Publication history
Accepted:
March 6,
1998
Received in revised form:
December 19,
1997
Received:
August 20,
1997
Identification
Copyright
© 1998 Elsevier Science Ireland Ltd. Published by Elsevier Inc. All rights reserved.
